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Formocresol, GlutaraldehydeÀÇ Á¢Ã˽𣿡 µû¸¥ ¼º°ßÄ¡¼öÀÇ º´¸®Á¶Á÷ÇÐÀû ¾ð±¸

A HISTOPATHOLOGICAL STUDY ON THE PULP TISSUE REACTIONS TO FORMOCRESOL AND GLUTARALDEHYDE AT THE DlFFERENT TIME INTERVA LS OF APPLICATION IN DOGS

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ÃÖº´Àç/Byung Jai Choi

Abstract

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ÀúÀÚ´Â »ýÈÄ ¾à1 ³âµÈ ¼º°ß¿¡¼­ formocresol, glutaraldehydeÀÇ Ä¡¼öÀý´Ü¸éÀÇ Á¢Ã˽ð£À»
1ºÐ, 3ºÐ, 5ºÐ, 3ÀÏ, 7ÀÏ·Î ³ª´©¾î Åë¹ý¿¡ µû¶ó Ä¡¼öÀý´Ü¼úÀ» ½ÃÇàÇÑ ÈÄ Ä¡¼öÁ¶Á÷ÀÇ º¯È­¸¦
º´¸®Á¶Á÷ÇÐÀûÀ¸·Î °üÂûÇÑ ¹Ù ´ÙÀ½°ú °°Àº °á·ÐÀ» ¾ò¾ú´Ù.
1. Formocresol 1ºÐ, 3ºÐ, 3ÀÏ, 7Àϱº°ú glutaraldehyde 1ºÐ, 3ÀÏ, 7ÀϱºÀÇ Ä¡¼ö¹ÝÀÀÀº Á¤»ó
Ä¡¼ö¼Ò°ßÀ¸·ÎºÎÅÍ Àü¹ÝÀûÀÎ ÀÀ°í¼º ±«»ç±îÁö ´Ù¾çÇÏ°Ô ³ªÅ¸³µ´Ù.
2. Formocresol 5ºÐ±º°ú g1utaraldehy-de 3ºÐ, 5ºÐ±ºÀº ´Ù¸¥±º¿¡ ºñÇÏ¿© ¿°ÁõÀÌ °æ¹ÌÇÏ¿´
À¸¸ç °ÅÀÇ Á¤»óÀûÀÎ Ä¡¼öÇüŸ¦ º¸¿´´Ù.
3. Formocresol ±º°ú glutaraldehyde±º¿¡¼­ ´ëºÎºÐ ¼öº¹»ó¾ÆÁúÀÌ Çü¼ºµÇ¾ú´Ù.
4. »ó¾ÆÁú Èí¼ö´Â glutaraldehyde ±ºº¸´Ù formocresol ±º¿¡¼­ ´õ ÀÚÁÖ °üÂûµÇ¾ú´Ù.
#ÃÊ·Ï#
The purpose of this study is to observe tile histopathological changes of the pulp
tissue after vital pulpotomy with fornlocresol or glutaraldehyde at the different time
intervals of application. Upper and lower teeth in seven dogs, aged about 1 years, were
subjected to pulp amputations and were divided into two groups, one of which was
pulpotonlized with formocresol, the other was with glutaraldehyde, The application was
perfornled at the intervals of 1 mlnute, 3 minutes, 5 minites, 3 days and 7 days, and
then the experimental animals were sacrificed 2 months after the last experiment.
The excised jaw bones were fixed in 10% neutral buffered fornlalin solutions, and
they were routinely decalcified in 5% nitric acid, and embedded in paraffin, and sections
were stained with henlatoxylin and rosin and observed with light microscope.
Following results were obtained .
1. In the formocresol 1 minute-, 3 minute-, 3 day- and 7 day- groups and the
glutaraldehyde 1 minute-, 3 day- and 7 day- groups, the pulp tissue responses varied
from normal pulp tissue findings to total coagulation necrosis.
2. In the formocresol 5 minute- group and the glutaraldehyde 3 minute- and 5
minute-groups, they showed slight inflamation and the almost typical morphology of
normal pulp tissue.
3. In the almost formocresol and glutaraldehyde groups, reparative dentin was formed.
4. Dentinal resorption in the formocresol group was more frequent than that in the
glutar-aldehyde group.

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